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Active HIV Research Studies

About this Page

This page hosts a collection of HIV and HIV-related research at the University of California San Diego and affiliated sites. Progress in treatment for HIV, hepatitis C, hepatitis B, tuberculosis, and other related conditions only occurs with the valuable contributions of individuals who enroll in research studies. These clinical research trials help improve the treatment and management of HIV and other infections. 

We encourage you to bookmark this page and check back often, as new opportunities to participate in HIV and related research are added frequently. 

This page is managed by The HIV Institute at the University of California San Diego. Contact us at hiv@ucsd.edu with any questions, feedback, or recommendations. Please note, inquiries regarding a specific study or sponsoring center should be directed to the contact listed. The HIV Institute does not manage any of these studies.

To see all HIV/AIDS clinical trials at UC San Diego (including those in progress as well as actively enrolling studies), please visit the UC San Diego Health Clinical Trials page.

If you are interested in including a research opportunity on this page, please click the button below to submit details.

Submit studies

*Disclaimer: Each sponsoring center and/or principal investigator is responsible for the studies listed on this website. This includes study preparation, conduct, and administration of a research grant, cooperative agreement, training or public service project, contract, or other sponsored project in compliance with applicable laws and regulations and institutional policy governing the conduct of sponsored research. Contact the indicated party listed below with any study-related questions.

Antiviral Research Center (AVRC)

To enroll in or get more information about one of these clinical trials at the AVRC, please call the Screening Coordinator at (619) 543-3740 or email Marvin Hanashiro at mhanashiro@health.ucsd.edu

Click here to see a full list of the Antiviral Research Center's currently enrolling studies.


CMV-specific HIV-CAR T cells as Immunotherapy for HIV (Research for an HIV Cure) 

The primary goal of this trial is to assess the safety of administering autologous CMV/HIV-CAR T cells to people with HIV. This includes a thorough evaluation of potential toxicities, their nature, frequency, severity, timing, and duration.

Click here for more information and eligibility requirements.
 HIV 


 LAST GIFT

People at the end of their lives often have a unique perspective on life, death and altruism, and may hold the keys to curing HIV. This study takes the next steps in finding a cure for HIV by understanding how reservoirs are distributed throughout the body.

Click here for more information and eligibility requirements.
 HIV


WE RISE (Women-focused Encounters for Resilience, Independence, Strength, and Eudaimonia)

An 8-week group-based exercise, therapy, and social support intervention focused on common concerns for women living with HIV (e.g. stigma, trauma, substance use).

Click here for more information and eligibility requirements.

  HIV


 PURPOSE-365 (Injectable PrEP Study)

We are conducting a clinical study to see whether an investigational twice-a-year injection medication can help reduce the risk of getting HIV from sex.

Click here for more information and eligibility requirements.
 HIV    SEXUAL HEALTH  

 

HIV Neurobehavioral Research Program (HNRP)

To enroll in or get more information about research studies at the HNRP, please call (619) 543-5000 and ask to speak with a research recruiter. 

You may be eligible to participate if you:
are at least 18 years old
are HIV+ or HIV- (do not have HIV)
do or do not have a history of substance use

For participating you will receive:
Monetary compensation
Lab results (at no cost to you)
Medical and psychological test results (upon request at no cost to you)

*All information obtained during the study is kept strictly confidential.


Cannabis Use, Cognition, and the Endocannabinoid System in HIV

Understanding how co-morbidities in persons with HIV (PWH) such as substance use affect risk-taking, decision-making, and other cognitive behaviors is important given implications for everyday functioning and transmission risk

Click here for more information and eligibility requirements

 HIV 

 

Mother Child Adolescent Program (MCAP)

To enroll or get more information about one of these IMPACT studies at MCAP, please email Study Coordinator: Alejandra Leon at a5leon@health.ucsd.edu

 

Owen Clinic

Check back soon for clinical trial updates for Owen Clinic.

Other UC San Diego HIV Research Studies

Visit this page for other UC San Diego research Studies.

 

Site last updated 11/19/25