Active HIV Research Studies

To enroll in or get more information about one of these clinical trials at the AVRC, please call the Screening Coordinator at (619) 543-3740 or email Marvin Hanashiro at mhanashiro@health.ucsd.edu

Click here to see a full list of the Antiviral Research Center's currently enrolling studies.

CMV-specific HIV-CAR T cells as Immunotherapy for HIV (Research for an HIV Cure) 

The primary goal of this trial is to assess the safety of administering autologous CMV/HIV-CAR T cells to people with HIV. This includes a thorough evaluation of potential toxicities, their nature, frequency, severity, timing, and duration.

Click here for more information and eligibility requirements.
 HIV 

 ACTG A5321 (AHRC) 

Studying differences and changes over time in HIV reservoirs (groups of HIV-infected cells that 'hide' from anti-HIV medications) and attempting to answer questions about the ways that HIV infection is controlled. This may have to do with a person’s viral load and CD4 count, when they started their anti-HIV medications, and genetic factors.
Click here for more information and eligibility requirements.

 HIV   

DEPTH (Doxycycline for Emphysema in People Living with HIV)

This is a research study to evaluate if the medication doxycycline, a commonly used antibiotic, can slow the damage to the lungs caused by emphysema in people who also have HIV. Emphysema is more prevalent in people living with HIV and may progress faster than in HIV-negative individuals.

Click here for more information and eligibility requirements.
 HIV 

 LAST GIFT

People at the end of their lives often have a unique perspective on life, death and altruism, and may hold the keys to curing HIV. This study takes the next steps in finding a cure for HIV by understanding how reservoirs are distributed throughout the body.
Click here for more information and eligibility requirements.
 HIV 

TRUVIAN

This research study seeks to test the performance of an investigational blood analyzer to make routine health tests convenient and get results fast. Eligible participants will receive $40 as compensation for a clinic visit and blood draw.

Click here for more information and eligibility requirements.

PURPOSE-3 (Injectable PrEP Study)

We are conducting a clinical study to see whether an investigational twice-a-year injection medication can help reduce the risk of getting HIV from sex.

Click here for more information and eligibility requirements.
 HIV    SEXUAL HEALTH  

PURPOSE-4 (Injectable PrEP Study)

​We are conducting a clinical study to see whether an investigational twice-a-year injection medication can help reduce the risk of getting HIV among people who inject drugs.

Click here for more information and eligibility requirements.
 HIV    SEXUAL HEALTH  

To enroll in or get more information about research studies at the HNRP, please call (619) 543-5000 and ask to speak with a research recruiter. 

You may be eligible to participate if you:
•are at least 18 years old
•are HIV+ or HIV- (do not have HIV)
•do or do not have a history of substance use

For participating you will receive:
•Monetary compensation
•Lab results (at no cost to you)
•Medical and psychological test results (upon request at no cost to you)

*All information obtained during the study is kept strictly confidential.

iSTEP - an mHealth Physical Activity and Diet Intervention for Persons With HIV

Summary: HIV is associated with a pattern of neurocognitive deficits, metabolic dysfunction, and an elevated risk for cardiovascular disease (CVD), phenomena that remain untreated despite the use of medications to control the disease. This proposal will examine the effect of a personalized, automated, interactive mobile phone text message intervention (iSTEP) designed to increase moderate physical activity (PA), decrease sedentary behavior (SB), and promote a healthy Mediterranean-style diet (MedDiet) in persons living with HIV (PLWH). The investigators propose that participants who receive the iSTEP intervention will increase the amount of physical activity, improve their diet, show a reduction in risk factors for CVD, and exhibit improved neurocognitive performance.
Click here for more information and eligibility requirements

 HIV 

DETECT: A novel device to assess how HIV affects neurocognitive decline and postural instability in older adults at risk for Alzheimer's Disease

This is a research study to determine if a brief virtual reality (VR) assessment among older adults living with HIV can help us better screen for changes in cognition and balance.

Click here to download information on this study

Email: hnrprecruitment@ucsd.edu for more information or if you are interested in enrolling
 HIV 

Biomarkers of Resilience and injury related to HIV and Methamphetamine (BRIHM)

This project will look at METH and HIV-associated biomarker signatures of CNS injury and resilience and will translate them to the clinical environment.

Click here to download information on this study

Email hnrprecruitment@ucsd.edu for more information or if you are interested in enrolling
 HIV 

Cross-species studies of smoking effects on cognition and neuroinflammation in HIV

This study will examine how smoking affects people living with HIV, specifically the function and performance of the brain.

Click here to download information on this study

Email: hnrprecruitment@ucsd.edu for more information or if you are interested in enrolling
 HIV 

iSEE Study

iSee is a dissertation study for black females. Individuals can be- English speaking, 18 years of age and older, self-identify as Black/African American, self-identify as a mothers, daughters, and receive compensation for their participation. View the enrollment flyer.

 HIV